(I have to give them baths with a very mild or medicated shampoo.) We actually live in New Hampshire and hike (off-leash) quite frequently. It makes me nervous since I have seen/read plenty of negative things about bravecto and Im also worried to combine bravecto with interceptor. However, the safety of Interceptor Plus has not been evaluated for pregnant or lactating dogs, and it is not recommended for cats. If your dogs arent reacting to it, why are you switching? No treatment-related clinical signs were observed. And safe travels to you and Lola in the future. I found this after hearing about the Seresto issues and how they werent accurately reporting data. I found some good information on the Cyphenothrin in Parastar Plus in this article. I have been told that Advocate is safe for him at the recommended dose. I doubt these would be cheaper than fipronil but it's worth checking. GSD is an abbreviation for German Shepherd Dog , Thankyou so much for your articleso much great infoI have a 7 month mini Aussieon Symparticabut not feeling good about itshe hasnt been tested for MRD1 but I know I have to change it upthankyou again , Youre very welcome, and good luck with your pup! Use These Products Infrequently, Only as Needed I found the same data during my search, but question if this information is skewed, because there is likely a much smaller group of dogs using Credelio. Congratulations and good luck with your new dog! I give Interceptor Plus for HW, but Im conflicted about which direction to go for flea & tick. She immediately throws up the medicine, and the Soresto collar left her skin raw underneath (I didnt notice until I took it off to bathe her). No toxicity was seen when affected dogs were given 28 to 35.5 mcg/kg monthly for one year. Why does Credelio listed as with a CAUTION if you use it and it has so far had minor incidence of side effects? The back label warns that it may be fatal for cats, and advises cats and dogs should be kept apart for 24 hours following application. Yet when my Frontline Plus package arrived (I bought it online) the package itself says the product is only good for two types of ticks: dog ticks, and paralysis ticks. Most pet parents give heartworm medications in conjunction with flea & tick medications, so Id have given Nexgard a caution label even before the FDA warning came out. I was using Seresto collars and am on the hunt for something else. If youre concerned about a possible hormonal imbalance being triggered by Effifax, it might be worth looking into an alternate flea control product that does not contain Fipronil. Good luck with the puppies, and I hope they get healthy soon. However, it would be best to have a veterinarian collect a skin scraping to examine under a microscope and determine whether skin irritation is caused by demodectic or sarcoptic mites, as the causes and treatments differ between the two types. Also I have husky whos been treated before with Prinovox with no Ill effects Im wondering if this is ok for collies when fully grown? Simparica is a flavored chewable solution for fast and effective treatment against fleas and ticks. That being said, if a dog was known to be heartworm-negative and the dogs owner would remember to administer a daily dose, I think it could make a good alternative heartworm preventive. Unacceptable for me) He is MDR1 clear. No adverse effects were observed. So it's very likely that the adverse effects of this chewable drug are similar to the other two drugs. As a drug in the isoxazoline class, all Simparica products should be used with caution in dogs with a history of seizures, epilepsy, or neurologic disorders. safe for dogs Approved for puppies as young as 8 weeks old weighing 2.8 lbs or more Highly palatable 1 liver-flavored chewable Can be given with or without food. Hello, You mentioned ADVANTIX should be use with caution because of cats being around collies, but what about if I only have collies? Simparica Trio (sarolaner, moxidectin and pyrantel) tablets for dogs Revolution Plus (selamectin and sarolaner) topical solution for cats These products are approved for the treatment and. Our are both indoors and outdoors. However, the medicine can be passed through a mothers milk: so it is not recommended for pregnant or nursing female dogs, though it is safe for puppies 8 weeks of age and older. Personally, my Roughs have sensitive skin plus I have a household cat, so Id try Frontline Gold first. Their treatment for this was nexgard and medicated baths. Ill list all the options I looked into (including several Ive personally tried), along with whether theyre considered safe to use, use with caution, or a complete no-no. My dog has been tested and is mutant/normal (MDR1). Simparica has not been evaluated in dogs that are pregnant, breeding or lactating. ProHeart 12 is made by Zoetis, Inc. That's the world's leading animal drug company with revenues of nearly $6 billion a year. ? Hi Emily, this is a great article and I appreciate all of your research! Get new post updates in monthly email newsletters. Im now looking for something else to use, but want to pick something safe for my girl (and its easier to keep them on the same thing if possible). The manufracturers website lists many different kinds of ticks, and people on this thread talk about using FrontLine for ticks. Bottom line is that Simparica will probably be fine for your dog, but there is a slight risk that it wont. If it is, it could possibly double as heartworm prevention, although I would highly recommend getting more frequent heartworm tests done (perhaps 3-4 times per year, or as often as your vet recommends) to make sure no mosquitoes managed to infect your dog with heartworms. Submit a story, ask a question, or just say hi; Emily would love to hear from you. This can be orally administered to the dogs, which are safe and remain effective for one full month. Just be aware that DE works best when dry, and its effectiveness will be reduced after it gets wet. This study investigated the safety of oral administration of fluralaner at 3 times the highest expected clinical dose to Multi Drug Resistance Protein 1 (MDR1(-/-)) gene defect Collies. My Aussie/Pyrenees mix has had no issues with it, for instance. Simparica TRIO (6.0 mg/0.12 mg/25. The amped-up version, Interceptor Plus, also contains praziquantel, which is used to treat tapeworms. My thought was to put on a collar in the morning and take it off at night when she will safely be back in the house. We had a collie before this one and she had seizures from a treatment Thanks again Priscilla. Dogs with the MDR1 mutation are not at increased risk for adverse effects. The rx I currently use on my dogs is serolaner (Simparica). Its simpler to identify medicines by their components, since many of them are essentially the same thing marketed under different brand names. This organic powder is great for a variety of uses. Some swear by food grade DE (diatomaceous earth) as a natural dewormer of roundworms, hookworms, whipworms, and even tapeworms. ProHeart 12 is not effective against adult D. immitis. Is Frontline Plus still safe? With complaints rolling in, the company made adjustments to the Ivermectin content in their product, and Heartgard is now advertised to be safe at the recommended dosage. But according to Dr. Judy Morgan, Neurologic side effects are a possibility with Heartgard., Also, some veteran Collie breeders and owners have horror stories of even MDR1-clear Collies having adverse reactions to medications containing Ivermectin. Of all the products you mentioned, I would prefer to try K 9 Advantix since it both repels and kills. Now we are out thousands of dollars when every event has been triggered by Simparica Trio. As with any topical product, monitor your pet for signs of skin irritation, and give them a bath within 24 hours to wash it off if signs of irritation are seen. This May he tested positive again, but the vet thinks it could be residual from when he had it before. And thank you for saying so. , Thanks for the reply! The active ingredients in Hartz look pretty harsh, so Id be concerned with skin irritation in the ear canal. If you choose to use Advantage Multi, great care should be taken to only apply the liquid between your dogs neck and shoulder blades, where it cannot be reached by licking. Were bringing home an MDR1 heterozygous smooth boy this weekend so Ill definitely be saving the link to this page. The most common side effect of Simparica is vomiting, which can happen within the first hour or two after administration. Plus, Simparica's protection lasts for five weeks (35 days), and it does not decrease at the end of the month. But it doesnt hurt mammals. Dr. Morgan concluded her story with: Be your pets advocate. But Ive given it a caution designation as it should not be given in combination with heartworm meds and is not safe for dogs who are at risk for seizures. From the time that the collar went on the market in 2012 until 2020, the EPA (Environmental Protection Agency) received 1,698 reports of deceased pets. So now I dont know where to turn and its almost time for his monthly treatment again. Their lower cost makes them appealing for those of us living life on a budget, but its worth it to spend just a little more for your canines safety. Some parts of the U.S. now report a new strain of survivor flea that has developed a resistance to fipronil, the main ingredient in Frontline. From the standpoint of MDR1 dogs, it is safe. Be prepared to answer questions about whether your dog had a previous history with seizures, has any drug sensitivities, if anything else could possibly have triggered a seizure, and if she has had any seizures since the collar was removed. Im just looking for advice as to tick prevention medication. Sentinel comes in a chewable pill form and protects against multiple internal parasites (heartworms, whipworms, hookworms, and roundworms) as well as the development of flea eggs. ), The lack of accessible information on the topic of safe parasite protection left me so frustrated that I decided to write my own article. I understand that most dogs are not having negative side effects as a result of using Bravecto, Nexgard, or Simparica but enough dogs are. Have you had any issues with Seresto? We will get her in about 3 weeks. Hi Emily I have two Miniature Australian Shepherds that are my entire world: Nola Riley and Otis Kai : ) Nola is MDR1-Heterozygous. I plan to switch him over to Trifexis also. Dec 26, 2017. . If you are able to keep your dogs separated from your cats for 24hrs, the added protection against mosquitoes that K9 Advantix II provides from the possible diseases they carry seems like a greater pro to con ratio. The product insert states Do not use this product on debilitated, aged, medicated, pregnant or nursing dogs, or dogs known to be sensitive to pesticide products., If you live in a seasonal region where you actually experience winter complete with freezing temperatures and snow, and your pets have been on regular pest preventive products, you can give them a break from chemicals for a few months while the insects are dormant. I been debating which one to use on my BC and small BC mix for ticks as well as prevention of Mites, which seem to increase in numbers with the ever increasing number of Coyotes we see these days. Thank you for the research and the detailed info on each product. When reading about Seresto, their website said it doesnt work well on dogs with heavy coats, ie. On the downside, its efficacy only lasts for about a day. I found a paper on the web written with credits to several vets. The product was well tolerated in dogs with a deficient multidrug-resistance-protein 1 (MDR1 -/-). Best of luck with your girl. Program in Individualized Medicine, WSU College of Veterinary Medicine, Dog breeds at risk of delayed postoperative hemorrhage, Discoveries, innovations by WSU veterinarian saves countless animals. Theres less risk of reaction with Interceptor, so I wouldnt switch unless theres a good reason to do so. Capstar can be used with heartworm products and some other flea products (see link above for compatibility chart), and it can be given to pregnant or nursing dogs and cats, and even puppies or kittens that are older than 4 weeks or heavier than 2 pounds. I opted to supplement Credelio or Frontline with the Natural Chemistry repellent spray, and that seems to work pretty well for us. You can also reach me through the contact form here on the website. Simparica Trio has the same main ingredient as regular Simparica, plus two added ingredients. We use interceptor for heartworms and was using frontline until she recently started having negative reactions to it. Regardless of the heartworm product you choose, as the Institute of Pharmacology and Toxicology says, treatment of MDR1 mutant dogs with macrocyclic lactones in general requires particular caution. It really boils down to weighing the benefits of medications against the risks from internal parasites. We gave her the first dose in late February and there were no adverse side effects for Sugar. ? I have a unique situation. Sugar is a great name for a Collie as they really are such sweethearts. However, it did make my Collies too itchy. Great summary! This is where this can get tricky with the MDR1 gene mutation. That indicates it is a strong chemical compound, so do watch for skin irritation.
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